For my specific flights, I'm flying out of Dublin (Terminal 2) which has US customs pre-clearance. I arrive in Atlanta before connecting to San Francisco. I'd like to shop at the duty free store in Dublin, but I don't want to risk having a bottle of whiskey with me in my carry-on luggage if I need to go through TSA security in Atlanta.
I'm flying on Delta.
EDIT: I actually got rebooked a bit, but my flight was treated as a domestic flight once in the US. I did go through a second security screening in Dublin, however, just prior to passing through customs.