Basically, €50 banknotes and smaller (including all the coins) are used in daily life all the time. Some stores may refuse to accept 200€ or 500€ banknotes (€100 is kinda in between). So the best idea is probably to bring your cash in €50 notes.
There is no €1 banknote, only coins. Some vending machines only take coins, but nothing important. You probably won't get Euro coins in your home country anyway.