I am an Indian citizen and will be traveling to USA on a B2 (tourist visa). Will I face additional scrutiny if I fly with Saudi Arabian airlines? The tickets are like $300 cheaper so. There is a 3 hour halt at Jeddah Intl airport, Saudi Arabia. Will I face problems at the port of entry in USA?
No; you will not.
You may face extra scrutiny based on your travel profile, but definitely not the airline - you also cannot "fix" your travel profile by flying on Emirates, Gulf, Etihad, Kuwait Airways or Qatar Airways in lieu of Saudi Arabian Airlines.
You will be scrutinized just as anyone else would based on your unique profile; the details of which are only privy to the authorities.
As long as you don't enter the country where your layover takes place, it doesn't matter how you travel from A to B. So just make sure to stay airside at the layover airport. What Border Patrol cares about is what countries you actually spent time in.