One big problem here is that deer, elk and moose can't read. They don't know or care about national park boundaries, highways, etc. And a moose can weigh half as much as your car; if you hit one, your car will probably be totaled - and the moose might even walk away!
If you'll watch that video (and this one), you'll note that collisions can even happen in daylight; the moose can literally come out of nowhere before you have a chance to see them. At night it's very possible you won't even know there is a moose there before you hit it, if it is looking away from you as you drive toward it.
Note that while there are more and less populated areas, you can find a moose virtually anywhere in Canada below the Arctic Circle. This includes within towns and cities, so don't let down your guard simply because you arrived in a town somewhere.
While roads in the areas with high moose activity will have warning signs, as I mentioned before, moose can't read and may try to cross the road practically anywhere. You should drive cautiously on this route even in the daytime.
If you do drive here at night, the advice I have heard given most often is to carry a passenger who can watch the roadway and help you spot animals who may be on or near the road. If you haven't got a passenger, watch for reflection from their eyes, which you may be able to see from a long way off.
The more general advice also applies:
- Wear your seat belt.
Watch both sides of the road. Many people make the mistake of mostly or only watching the right side of the road, especially on motorways like the Trans-Canada Highway. But animals can easily cross the median.
(And note that this highway is dual carriageway in Alberta, but becomes a two-lane single carriageway when you cross into British Columbia.)
Drive more slowly, 90kph or less, to give you more ability to stop and take evasive action, and to reduce the impact of a collision.
- If you think there may be an animal ahead, turn off your high beam headlights and slow down further.
- In places which do have signs, be extra cautious, as these are the areas with the highest levels of activity.
- Be extra cautious at dawn and after dusk. These are the times large animals are most active.
- Keep your car centred in the carriageway as much as possible, to give you more options for evasive action.
- If an animal does appear in front of you, just slam on the brakes. If you swerve, you may collide with other traffic (or another animal!) or lose control of your vehicle.
Also note that British Columbia authorities publish advice regarding wildlife on their drivebc.ca website.