I booked a weekend trip to Prague from may 24th until the 26th and just discovered that there will be a running event like a marathon. Will the city be accessible? And if not, what are the best places to visit on such a day? Our hotel is near the center of Mala Strana.
Which running event would that be? I looked at several event calendars for Prague, and they all list only a marathon on May 11th.
In any case, I wouldn't be concerned; you're in walking distance of lots of sights, and the metro shouldn't be affected by such events anyway.