After my last intercontinental flight (8 hours difference between arrival and departure airport) I used melatonin to cope with jet lag and it worked pretty fine. I was able to have some decent sleep, without being awake overnight.
For my next trip on the same route, I am wondering if taking melatonin during the flight would be advisable or are there any reason why I should avoid it.
I am flying as passenger, not as crew member, and the departure time is in the early afternoon (evening at destination). So I was thinking that taking melatonin shortly after departure would set me on the "right" time zone one day earlier.