My wife was just issued a multiple entry visa by France, which is good for one year. Our first trip will be to France, the issuing country. My question is: after we leave the EU and return, must future trips also start in France? Or may we go directly to (say) Greece from the US on a later visit?
You can enter any country within the Schengen area (25 countries) with no problems. Check the Schengen visa website. I have done that personally before.
Anyway, Out of personal experience, German immigration are not really friendly with this idea. Once in Frankfurt they refused the entry of a friend to the country because she had her visa issued from the Italian Embassy. Anyway after few tears they let her in. Moral of the story, Yes you can enter any Schengen country with your Schengen visa regardless of the issuing country.
protected by Ankur Banerjee♦ Jun 5 '13 at 7:20
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