I consider a holiday in Brazil, especially Florianópolis. But I can't speak any Portuguese.
Can I get around there with English and a little Spanish?
I spent a few months in Brazil, I didn't speak any Portuguese and my Spanish is not that good either. So it didn't help me understanding people, but it helped a little reading signs, and they could almost always understand my basic Spanish.
It really depends on where you are going and how deep you want to get into the local culture.
I've been to many countries where I did not speak the local language and hardly anybody spoke English, plus all signs were written in a different alphabet. And still, I got around just fine. In Brazil you can at least read the names of the places you want to go to. In most hotels/hostels there is someone speaking English, and if not it still works. Your food, accommodation and transport needs work out somehow. Where it gets a bit more tricky is when you have special needs, say you need to see a doctor.
Brazil was pretty easy and there are many people who speak English and could help out.
I managed to get around just fine when I moved there. English is more widely spoken in the larger cities than in smaller towns. Spanish is spoken some near the western borders. But in any case, a large smile and gestures along with using a phrase book will get you a very long way.
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